Vaccine Protocols

Information and templates for writing a vaccine administration order, also called a protocol.

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On this page:

Guidance Documents

• Guidance for Adopting Vaccine Protocols (PDF)
  Information on why vaccine protocols are necessary, why there are so many protocols, annual signing of protocols, and how to get started.
• CDC: Vaccine Exipient Summary
  List excipients included in U.S. vaccines, by vaccine, to help determine potential allergens.

Supporting Resources

• Immunize.org: Guide to Contraindications and Precautions to Commonly Used Vaccines (PDF)
  Guide designed to help immunization providers determine what common symptoms and conditions should contraindicate vaccination and which ones should not.
• CDC: Vaccine Recommendations and Guidelines for Timing and Spacing of Immunobiologics
  Best practice guidance of the Advisory Committee on Immunization Practices (ACIP).

Vaccine Protocol Templates

Vaccine protocol templates to be filled in and used.

COVID-19

• 2024-2025 Moderna COVID-19 Vaccine for Age 6 Months to 11 Years (Word) Updated 11/05/24
• 2024-2025 Moderna COVID-19 Vaccine for Age 12 Years and Older (Word) Updated 11/05/24
• 2024-2025 Novavax COVID-19 Vaccine, Adjuvanted Protocol (Word) Updated 11/05/24
• 2024-2025 Pfizer-BioNTech COVID-19 Vaccine for Age 6 Months to 4 Years (Word) Updated 11/05/24
• 2024-2025 Pfizer-BioNTech COVID-19 Vaccine for Age 5 to 11 Years (Word) Updated 11/05/24
• 2024-2025 Pfizer-BioNTech COVID-19 Vaccine for Age 12 Years and Older (Word) Updated 11/05/24

DTaP

• Diphtheria, Tetanus, and Pertussis (DTaP) Routine and Catch-up Vaccine Protocol (Word) Updated 03/26/24

DTap-IPV

• Combination Diphtheria, Tetanus, and Pertussis - Polio (DTap-IPV) Vaccine Protocol (Word) Updated 03/26/24

DTaP-IPV-Hep B

• Combination Diphtheria, Tetanus, and Pertussis - Polio - Hepatitis B (DTaP-IPV-HepB) Routine and Catch-up Vaccine Protocol (Word) Updated 03/26/24

DTap-IPV-Hib

• Combination Diphtheria, Tetanus, and Pertussis - Polio - Haemophilus influenza, Type B (DTap-IPV-Hib) Routine and Catch-up Vaccine Protocol (Word) Updated 03/26/24

DTaP-IPV-Hib-Hep B

• Combination Diphtheria, Tetanus and Pertussis – Polio – Haemophilus influenza, type B – Hepatitis B (DTaP-IPV-Hib-HepB) Routine and Catch-up Vaccine Protocol (Word) Updated 03/26/24

Hepatitis A

• Hepatitis A (Hep A) Routine, Catch-up and At-risk Vaccine Protocol (Word) Updated 06/06/23

Hepatitis A and Hepatitis B (Twinrix)

• Hepatitis A and Hepatitis B as Twinrix Vaccine Protocol (Word) Updated 06/06/23

Hepatitis B

• Hepatitis B (Hep B) Routine Infant Vaccine Protocol (Word) Updated 06/06/23
• Hepatitis B (Hep B) Catch-up Vaccine Protocol (Word) Updated 06/06/23
• Hepatitis B (Hep B) Adult Vaccine Protocol (Word) Updated 06/06/23

Hib

• Haemophilus Influenza, Type B (Hib) Routine and Catch-up Vaccine Protocol (Word) Updated 06/06/23

HPV

• Human Papillomavirus Routine and Catch-up Vaccine Protocol (Word) Updated 06/06/23

Influenza

• Inactivated Influenza Vaccine (IIV) Protocol Children Age 6 Months Through 8 Years (Word) Updated 08/28/24
• Inactivated Influenza Vaccine (IIV) Protocol Persons Age 9 Years and Older (Word) Updated 08/28/24
• Live Attenuated Influenza Vaccine (LAIV) Vaccine Protocol (Word) Updated 08/28/24

Meningococcal

• Meningococcal B Vaccine Protocol (Word) Updated 11/05/24
• Meningococcal ABCWY Vaccine Protocol (Word) Updated 05/07/24
• Meningococcal Conjugate Vaccine, 4-Valent (MCV4) for Routine, Catch-up, At-risk and Booster Dose Vaccine Protocol (Word) Updated 06/06/23

MMR and MMRV

• MMR Routine and Catch-up Vaccine Protocol (Word) Updated 06/06/23
• Combination Measles, Mumps, Rubella, and Varicella (MMRV) Routine and Catch-up Vaccine Protocol (Word) Updated 06/06/23

Orthopox (mpox)

• Orthopox Vaccine Protocol: JYNNEOS Updated 08/26/24

Pneumococcal

• Pneumococcal Conjugate Vaccine, 15-Valent (PCV15) Vaccination: Vaccine Protocol for Persons Age 19 or Older (Word) Updated 11/05/24
• Pneumococcal Conjugate, 20-valent (PCV20) Routine, Catch-up & At-Risk Vaccine Protocol for Persons 6 Weeks to Age 18 Years (Word) Updated 09/28/23
• Pneumococcal Conjugate Vaccine, 20-Valent (PCV20) Vaccination: Vaccine Protocol for Persons Age 19 Years or Older (Word) Updated 11/05/24
• Pneumococcal Conjugate Vaccine, 21-Valent (PCV21) Vaccination: Vaccine Protocol for Persons Age 19 Years or Older (Word) Updated 11/05/24
• Pneumococcal Polysaccharide Vaccine, 23-Valent (PPSV23) Vaccination: Vaccine Protocol for Persons Age 19 Years or Older (Word) Updated 11/05/24
• Pneumococcal Polysaccharide Vaccine, 23-Valent (PPSV23) Vaccination: Vaccine Protocol for At-risk Persons Age 2-18 Years (Word) Updated 04/28/22

Refer to Pneumococcal Vaccination: Summary of Who and When to Vaccinate for more guidance and tools, including a mobile app and "Pneumococcal Vaccine Timing for Adults" printable handout.

Polio

• Inactivated Polio Vaccine (IPV) for Routine, Catch-up and Booser Dose Vaccine Protocol (Word) Updated 04/18/24

Rotavirus

• Rotavirus Routine and Catch-up Vaccine Protocol (Word) Updated 06/06/23

RSV

• Respiratory Syncytial Virus (RSV) Vaccine Protocol (Word) Updated 08/29/24
• Nirsevimab (Beyfortus) Protocol (Word) Updated 10/03/23

Tdap and Td

• Tetanus and Diphtheria (Td) Vaccine Protocol for Children Less Than Age 7 with Contraindication to Pertussis-containing Vaccine (Word) Updated 03/26/24
• Tetanus and Diphtheria Toxoids and Acellular Pertussis (Tdap) and Tetanus and Diphtheria (Td) Routine, Catch-up and Booster Dose Vaccine Protocol (Word) Updated 06/06/23

Varicella and MMRV

• Varicella Routine, Catch-up and Post Exposure Prophylaxis Vaccine Protocol (Word) Updated 06/06/23
• Combination Measles, Mumps, Rubella, and Varicella (MMRV) Routine and Catch-up Vaccine Protocol (Word) Updated 06/06/23

Zoster

• Recombinant Zoster Vaccine (RZV) Routine and At-risk Vaccine Protocol (Word) Updated 06/06/23